研究方向
医疗影像装备及算法开发
高分辨工业质量影像检测装开发
机器人自动化控制算法研究
人工智能算法研究
团队成果
2025
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16.发明专利授权：光学相干层成像中B-scan图像对准方法及系统
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15.发明专利授权：OCT图像超分辨率重建方法、系统、产品、介质及设备
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14. 文章发表：Optical coherence tomography angiography integrating differential phase and intensity images for in vivo imaging of a mouse retina. Optics Letters，2025
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13.发明专利授权：多尺度视频预测方法、系统、介质、产品及设备
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12.文章发表：Phase-compensated Differential Optical Coherence Tomography Angiography Algorithm Based on Frequency-domain Scale-Decorrelation Information Fusion, Optics Communications, 2025
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11.发明专利授权：一种可见光光纤旋转连接器及其校准方法
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10.文章发表：Method for Measuring Retinal Capillary Blood Flow Velocity by Encoded OCTA, Chinese optics letters. 2025
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9.发明专利授权：血流速度计算方法、OCT系统、介质、产品及设备
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8.发明专利授权：光谱反射率测试方法、OCT系统、介质、产品及设备
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7.发明专利授权：毛细血管光滑程度判定方法及装置
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6.发明专利授权：基于OCT成像的盲孔内表面缺陷检测方法及系统
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5.发明专利授权：基于渐变式陶瓷插芯的光纤端面距离校准的装置及方法
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4.发明专利授权：信号调制方法、OCT图像轴向超分辨率重建方法及系统
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3.发明专利授权：视网膜图像采集系统、方法、介质、产品及设备
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2.文章发表：Fusing Multispectral Information for Retinal Layer Segmentation, npj digital medicine, 2025
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1.文章发表：Leveraging Spectrum to Enhance the Accuracy of Retinal Layer Segmentation, 2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2024.
2024
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39.文章发表：A Dual-branch Multidomain Feature Fusion Network for Axial Super-resolution in Optical Coherence Tomography, IEEE Signal Processing Letters, 2025
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38.文章发表：A Review of Application of Deep Learning in Endoscopic Image Processing, Journal of Imaging,2024
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37.发明专利授权：基于OCTA 的毛细血管血流流速测量方法及系统
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36.发明专利授权：一种基于OCTA 编码的毛细血管流速测量方法及系统
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35.发明专利授权：去相关融合的OCTA图像处理方法、系统、设备及介质
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34.发明专利授权：用于毛细血管血流速度测量的多路OCT 系统及方法
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33.发明专利授权：一种可见光OCT人眼对焦和成像装置及方法
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32.发明专利授权：一种OCT自动寻找视网膜视神经头的方法、系统及产品
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31.发明专利授权：数字色散补偿方法及系统
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30.发明专利授权：扫描速度自适应控制方法、血流速度测量方法及测试装置
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29.文章发表：Recent Progress of Electrospun Nanofiber Dressing in the Promotion of Wound Healing,Polymers,2024
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28.发明专利授权：基于OCT深度信息的实时速度补偿方法及系统
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27.发明专利授权：一种高分辨率跳跃式多波段光谱仪及工作方法
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26.文章发表：可见光光学相干层析成像技术发展综述（特邀），中国激光，2024
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25.文章发表：MT Net: A Multi-Scale Framework Using the Transformer Block for Retina Layer Segmentation,Photonics,2024
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24.发明专利授权：一种定量装车的方法
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23.发明专利授权：一种轮径测量仪定位块磨损误差矫正方法及系统
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22.发明专利授权：自适应控制扫描距离的方法及装置
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21.发明专利授权：基于OCT的大视场流水线检测控制方法及系统
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20.发明专利授权：一种粮食扦样机及方法
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19.发明专利授权：一种OCT眼底成像装置及方法
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18.发明专利授权：一种基于实时成像的磨痂系统及方法
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17.文章发表：Light-weight Retinal Layer Segmentation with Global Reasoning, IEEE Transactions on Instrumentation and Measurement,2024.
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16.发明专利授权：基于双光谱仪进行光源噪声补偿的可见光OCT系统
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15.发明专利授权：基于双光谱仪探测的可见光OCT系统及图像重建方法
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14.发明专利授权：基于直方图信息网络的OCT轴向超分辨率方法及系统
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13.发明专利授权：一种大视场可见光OCT的双波段成像系统及方法
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12.发明专利授权：对焦组件、间歇对焦扫描且自动对焦的OCT装置及方法
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11.发明专利授权：可变焦距的共路型柔性内窥OCT系统及工作方法
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10.发明专利授权：一种皮肤撕脱伤血运检测方法、系统及OCT血运检测系统
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9.发明专利授权：扦样杆受力异常控制方法、系统、介质及电子设备
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8.发明专利授权：一种应变片外观缺陷检测方法及系统
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7.发明专利授权：一种双波段光谱仪及OCT成像系统
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6.发明专利授权：应用于轨道式双车道扦样机的粮车停放定位方法及系统
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5.发明专利授权：一种降低对焦时人眼注视疲劳的可见光OCT装置及方法
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4.发明专利授权：一种K域光谱仪棱镜的设计方法
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3.发明专利授权：基于OCT的活体原位实时活检针、装置及系统
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2.发明专利授权：一种自动避让血管手术刀系统
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1.发明专利授权：一种针刀主动避让血管系统
2023
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6.发明专利授权：一种光谱仪自动校准装置及方法
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5.发明专利授权：一种色散补偿调节方法及系统
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4.发明专利授权：基于多可见光光谱OCT影像的视网膜层分割方法及系统
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3.文章发表：Analysis of wear mechanism and sawing performance of carbide and PCD circular saw blades in machining hard aluminum alloy, International Journal Of Refractory Metals And Hard Materials,2023.
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2.发明专利授权：一种多传感器轮径测量仪及测量方法
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1.文章发表：Exploiting multi-granularity visual features for retinal layer segmentation in human eyes, Frontiers in Bioengineering and Biotechnology, 2023.
2022以前
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文章发表：Visible Light Optical Coherence Tomography of Peripapillary Retinal Nerve Fiber Layer Reflectivity in Glaucoma，Translational Vision Science & Technology，2022
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文章发表：The architecture of kinesin-3 KLP-6 reveals a multilevel-lockdown mechanism for autoinhibition, Nature Communications, 2022
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文章发表：A Baseline Study of Oxygen Saturation in Parafoveal Vessels Using Visible Light Optical Coherence Tomography, Frontiers in Medicine, 2022
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文章发表：Quantification of Corneal Collagen Cross-Linking in Keratoconus with Inverse Spectroscopic Optical Coherence Tomography, Investigative Ophthalmology & Visual Science, 2021
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文章发表：Deep-learning Augmented Reflectance Microscopy for Label-free Multiplexed Cytometry, CLEO: Applications and Technology, 2021
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文章发表：Single-cell cytometry via multiplexed fluorescence prediction by label-free reflectance microscopy, Science advances, 2021
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文章发表：Wide-field visible light optical coherence tomography (WF-vis-OCT) for human retinal imaging with axial-tracking and dynamic focusing, Investigative Ophthalmology & Visual Science, 2020
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文章发表：Visible light optical coherence tomography angiography (vis-OCTA) facilitates local microvascular oximetry in the human retina, Biomedical optics express, 2020
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文章发表：Is oblique scanning laser ophthalmoscope applicable to human ocular optics? A feasibility study using an eye model for volumetric imaging, Journal of biophotonics, 2020
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文章发表：Visible and near-infrared optical coherence tomography (vnOCT) in glaucoma suspect, pre-perimetric, and perimetric glaucoma, Investigative Ophthalmology & Visual Science, 2020
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文章发表：Evaluation of Ocular Surface Lesions by Inverse Spectroscopic Optical Coherence Tomography In Vivo, Investigative Ophthalmology & Visual Science, 2020
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文章发表：Synthesis and characterization of LiLuF4:Er3+ and LiLuF4:Yb3+,Er3+ exhibiting upconversion fluorescence pumped by a 1560 nm laser, New Journal of Chemistry, 2020
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文章发表：LED array reflectance microscopy for scattering-based multi-contrast imaging, Optics letters, 2020
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文章发表：Review of Advances in Ophthalmic Optical Imaging Technologies from Several Mouse Retinal Imaging Methods, Chinese Journal Of Lasers, 2020
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文章发表：Longitudinal detection of retinal alterations by visible and near-infrared optical coherence tomography in a dexamethasone-induced ocular hypertension mouse model, Neurophotonics, 2019
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文章发表：Volumetric fluorescein angiography (vFA) by oblique scanning laser ophthalmoscopy in mouse retina at 200 B-scans per second, Biomedical Optics Express, 2019
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文章发表：Quantitative quality-control metrics for in vivo oximetry in small vessels by visible light optical coherence tomography angiography, Biomedical Optics Express, 2019
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文章发表：Measurement of flow-mediated dilation of mouse femoral artery in vivo by optical coherence tomography, Journal of biophotonics, 2018
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文章发表：Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (OSLO) and Optical Coherence Tomography (OCT), Journal of Visualized Experiments: Jove, 2018
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文章发表：Fiber-based visible and near infrared optical coherence tomography (vnOCT) enables quantitative elastic light scattering spectroscopy in human retina, Biomedical Optics Express, 2018
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文章发表：Volumetric fluorescence retinal imaging in vivo over a 30-degree field of view by oblique scanning laser ophthalmoscopy (oSLO), Biomedical Optics Express, 2017
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文章发表：Mesoporous Carbon Nanospheres as a Multifunctional Carrier for Cancer Theranostics, Theranostics, 2018
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文章发表：Noninvasive Retinal Optical Imaging in Metabolic Diseases Mouse Models Using Optical Coherence Tomography, Free Radical Biology and Medicine, 2017
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文章发表：Wavelength-dependent optical properties of melanosomes in retinal pigmented epithelium and their changes with melanin bleaching: a numerical study, Biomedical optics express, 2017
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文章发表：Oblique scanning laser microscopy for simultaneously volumetric structural and molecular imaging using only one raster scan, Scientific reports, 2017
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文章发表：Enhanced Red Upconversion Luminescence in Yb-Er Codoped NaYF4 Nanocrystals, Journal of nanoscience and nanotechnology, 2016
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文章发表：Gain Characteristics of Polymer Waveguide Amplifiers Based on NaYF4:Yb3+, Er3+ Nanocrystals at 0.54 μm Wavelength, Journal of nanoscience and nanotechnology, 2016
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文章发表：The Effect of Phase Structures on the Enhanced Red Upconversion Luminescence in NaLuF4:Yb-Er Nanocrystals, Journal of Nanoscience and Nanotechnology, 2016
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文章发表：Synthesis of mesoporous-silica-coated Gd2O3:Eu@silica particles as cell imaging and drug delivery agents, Dalton Transactions, 2016
新闻动态
宋维业
工学博士，现为山东大学机械工程学院教授，博士生导师，山东省泰山学者青年专家，齐鲁青年学者。
研究领域
• 基于弱相干光学成像，光谱学分析等技术的光机电一体化医疗装备。
• 内窥镜。
• 医疗早期诊断、术中导航设备 。
•工业检测与质量控制，光学成像与机器视觉，光电检测设备。
国内外学习和工作经历
• 2021-至今 山东大学机械工程学院，教授，博士生导师
• 2020-2021 哈佛大学/麻省总医院 博士后
• 2016-2020 波士顿大学/波士顿医疗中心 博士后
• 2011-2016 吉林大学 物理电子学 博士
• 2006-2010 吉林大学 微电子学 本科
学术兼职
• 美国光学学会会员
• 视觉与眼科研究协会会员
• 中欧高层次人才交流中心 理事长
• 山东省生物医学工程学会专委会委员
• 山东省生物医学光子学会委员
• 山东省医疗数字孪生专委会委员
• 长期担任Journal of Biophotonics, Neurophotonics, Scientific Reports, Optics Express, Biomedical, Optics Express等期刊审稿人
团队成员
联系我们
地址：山东济南市历下区经十路17923号山东大学(千佛山校区)
